Django is a great Python framework to quickly build (web)applications.
Install your Django application on a Debian (Ubuntu) server
Install the Apache 2 mod_wsgi module and Django (if you don't have it installed already):
apt-get install libapache2-mod-wsgi python-django
You might also want to install mysql-server-core and maybe python-mysqldb. Also, python-django-dmigrations might be a handy Django package, as it is an improved 'syncdb' command [dmigrations project page].